BDBM18786 5-(3-chlorophenyl)-6-(3-phenylpropyl)pyrimidine-2,4-diamine::CHEMBL21921::P31
SMILES Nc1nc(N)c(c(CCCc2ccccc2)n1)-c1cccc(Cl)c1
InChI Key InChIKey=CZDYZPVAAIFLQU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 18786
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center For Genetic Engineering and Biotechnology At Thailand
National Center For Genetic Engineering and Biotechnology At Thailand
Affinity DataKi: 1.32nM IC50: 1.39E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair